Saccharopolyspora bacteria

Saccharopolyspora is a genus of gram-positive bacteria whose spores are round to oval and covered by a sheath. Members of this genus are characterized by the absence of mycolic acids (long-chain α-substituted Β-hydroxylated fatty acids) in the cell wall.[3]

  • Saccharopolyspora spinosa - Produces spinosyns A and D macrolide antibiotics. The combination of these substances serves as the active ingredient in a commercial insecticide, Naturalyte. This mixture exhibits excellent insecticidal activity with low mammalian toxicity and little detrimental environmental effects.[1]
  • Saccharopolyspora erythraea - Makes erythromycin, an antibiotic coliLI>Saccharopolyspora rectivirgula - Has been implicated of causing hypersensitivity pneumonia, also called allergic alveolitis or "farmer's lung" disease; it is believed that excess exposure to grain dust increases the risk for this disease.[2]


  1. The Biosynthesis of Spinosyn in Saccharopolyspora spinosa: Synthesis of the Cross-Bridging Precursor and Identification of the Function of SpnJ Hak Joong Kim et al
  2. Where Asthma and Hypersensitivity Pneumonitis Meet and Differ Noneosinophilic Severe Asthma Pieter Bogaert et al.
  3. Encyclopedia of Microbiology by Martin Alexander, Barry R. Bloom


Gram-negative Bacteria

Gram-positive Bacteria

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