Nephrotic syndrome is an abnormal kidney condition marked by excess protein in the blood, disbalance of body fats, and edema (swelling of body tissues). Other symptoms include weakness and loss of appetite. A physical examination may reveal a sudden or slow accumulation of fluid in the tissues of the arms and legs.
Causes of Nephrotic Syndrom
Acute or chronic glomerulonephritis may result in the disorder. Also, any abnormality that causes an increase in the pressure of blood in the veins leaving the kidney tissue. This can happen in heart failure or following a thrombosis in the renal vein.
Nephrotic syndrome may be a result of some systemic disease, such as amyloidosis, diabetes mellitus, or myeloma. It may also be caused by an allergic reaction to drug treatment. In rare cases, the disorder may be present at birth.
Treatment of Nephrotic Syndrom
Nephrotic syndrome requires careful and skilled attention from a specialist in kidney disease. The more serious cases make treatment difficult and the outcome may be fatal. Corticosteroid drugs may be useful as well as diuretic drugs to increase urine flow and reduce edema, but they do not treat the underlying cause.